Peter M. Henson, MD, BVMS, PhD

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Peter M. Henson

Peter M. Henson, MD, is a researcher at National Jewish Health. Dr. Henson is in the Division of Cell Biology and Department of Pediatrics.

Research Areas

  • Allergy
  • Basic Immunology
  • Cellular and Molecular Biology
  • Inflammation
  • Lung Cell Biology
  • Mycobacterial and Respiratory Infections
  • Pathology
  • Pulmonary Medicine
  • Regenerative Medicine

Special Interests

Innate immunity, experimental pathology, Inflammation and inflammmatory respiratory diseases

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Education

Education

1964 - 1967
University of Cambridge, PhD
1963 - 1964
University of Edinburgh, Bsc with Honors, Microbiology
1958 - 1963
University of Edinburgh, BVM&S

Fellowship

1967 - 1969
Scripps Research Institute, Experimental Pathology

Awards & Recognition

2011: Distinguished Professorship, University of Colorado
2005: Burns Amberson Lecture, ATS Centenary Meeting
1991: Margaret A. Regan Professor of Pulmonary Inflammation
1983: Reticuloendothelial Society, Marie T. Bonazinga Award
1980:American Association of Pathologists, Parke Davis Award

Publications

Fadok VA, Voelker DR, Campbell PA, Cohen JJ, Bratton DL and Henson PM. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol. 148(7):2207-2216, 1992.

Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGFβ, PGE2, and PAF. J. Clin. Invest. 101:890-898, 1998.  Huynh, M-LN, Fadok VA, Henson PM. Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGFβ1 secretion and resolution of inflammation. J Clin Invest 109:41-50, 2002.

Gardai S.J, McPhillips KA, Frasch SC, Janssen W.J, Starefeldt A, Murphy-Ullrich JE, Bratton DL, Oldenborg PA, Michalak M, Henson PM. Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte. Cell 123:321-334, 2005.

Gardai SJ, Xiao Y-Q, Dickinson M, Nick J, Voelker D, Greene K, Henson P. By binding SIRPα or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation. Cell. 115:13-23, 2003.

Desch AN, Gibbings SL, Clambey ET, Janssen WJ, Slansky JE, Kedl RM, Henson PM, and Jakubzick C. Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction. Nature communications, 5:4674 2014.

Academic Affiliations

Professor, Departments of Immunology and Microbiology, Medicine, Pharmacology, University of Colorado Denver

Teaching & Professional Positions

Associate Director, Pulmonary and Critical Care Fellowship Program
Member, Immunology Graduate Program Steering Committee

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