Redente Laboratory

Search Clinical Trials

Complete List of Published Work in My Bibliography

  1. Cooley JC, Penick SK, Wilson JA, Javkhlan N, Foster DG, Edelman BL, Schott CA, Humphries SM, Lynch DA, Schwartz DA, Riches DWH, Redente EF. Nintedanib Increases BCL-2 in Fibrotic Fibroblasts Enhancing ABT-199 Apoptosis and Fibrosis Resolution. Am J Respir Cell Mol Biol. 2026. Accepted for Publication.
  2. Redente EF, Song T, Javkhlan N, Edelman BL, Foster DG, Wilson JA, Chakraborty S, Cooley JC, Gaurav R, Saguthi S, Seibold MA, Blumhagen RZ, Schwartz DA, Yang IV, Matsuda J, Bridges JP, Zemans RL, Tuder RM, and Riches DWH. Conditional BCL-2 Expression in Fibroblasts Promotes Persistent Pulmonary Fibrosis, which is Reversible by Therapeutic BCL-2 Inhibition. Nat Comm. 2026. Feb 28. PMID: 41762163.
  3. Kim SH, Nouws J, Ruwisch J, Woodard G, Cooley J, Khoury J, Sun H, Doherty E, Piecychna M, Manning E, Kang MJ, Bruscia E, Wei H, Zhang Y, Yarovinsky T, Hwa J, Zacharias W, Ingram J, Lee CG, Elias J, Kaminski N, Redente EF, Herzog E, Prasse A, Bucala R, Sauler M. Dysregulated alveolar epithelial cell type 2 proteostasis promotes fibrogenic MIF-CD74 signaling in macrophages. Sci Trans Med. 2025. Dec 3;17(827):eadr2277. PMID: 41337540.
  4. Lee E, Williams KJ, McCarthy CC, Bridges JP, Redente EF, Vallim TQA, Barrington RA, Wang TF, Tarling EJ. Alveolar macrophage lipid burden correlates with clinical improvement in patients with Pulmonary Alveolar Proteinosis. Journal of Lipid Research. 2024 Jan 5:100496. PMID: 38185217.
  5. O’Callaghan M, Duignan J, Tarling EJ, Waters D, McStay M, O’Carroll O, Bridges JP, Redente EF, McGrath E, Butler MW, Fabre A, Murphy DJ, Keane MP, McCarthy C. Computed tomography pulmonary fat attenuation volume (PFAV) as a novel biomarker of idiopathic pulmonary fibrosis. Respirology. 2023 Nov;28(11):1043-1052. PMID: 37642207.
  6. Wang F, Ting C, Douglas M, Foster K, Patel N, Kaku N, Riemondy KA, Linsalata A, Jean Nemzek, Varisco BM, Wilson JA, Cohen E, Riches DWH, Redente EF, Toivola DM, Zhou X, Moore BB, Coulombe PA, Omary MB, Zemans RL. Regulation of the alveolar epithelial transitional state in murine and human pulmonary fibrosis. J Clin Invest. 2023 Nov 15;133(22):e165612. PMID: 3776873.
  7. Redente EF, Kopf KW, Bahadur AN, Robichaud A, Lundblad LK, McDonald LT. Application-specific Approaches to MicroCT for Evaluation of Mouse Models of Pulmonary Disease. PloS ONE. 2023 Feb 9;18(2):e0281452. PMID: 36757935.
  8. Cooley JC, Javkhlan N, Wilson JA, Foster DG, Edelman BL, Ortiz LA, Schwartz D, Riches DWH, Redente EF. Inhibition of anti-apoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis and reverses persistent pulmonary fibrosis. JCI Insight. 2023 Feb 8;8(3):e163762. PMID: 36752201.
  9. Redente EF, Black BP, Backos DS, Bahadur AN, Humphries SM, Lynch DA, Tuder RM, Rubin, Zemans RL, Riches DWH. Persistent, Progressive Pulmonary Fibrosis and Epithelial Remodeling in Mice. Am J Respir Cell Mol Biol. 2021 Jun;64(6):669-676. PMID: 33406369.
  10. Redente EF, Chakraborty S, Sajuthi S, Black BP, Edelman BL, Seibold MA, et al. Loss of Fas-signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis. JCI Insight. 2020 Dec 8;6(1):e14161. PMID: 33290280.
  11. Bamberg A*, Redente EF*, Groshong SD, Tuder RM, Cool CD, Keith RC, Edelman BL, Black BP, Cosgrove GP, Wynes MW, Curran-Everett D, De Lang S, Ortiz LA, Thorburn A, Grusby MJ, Riches DWH. The protein tyrosine phosphatase PTPN13 links lung fibroblast resistance to apoptosis with the development of pulmonary fibrosis. Am J Respir Crit Care Med. 2018 Oct 1;198(7):914-927. PMID: 29727583.
Search Clinical Trials