Grant Support
S10-RR031832
06/15/11 - 06/14/12
NIH-NCRR (PI Schwartz)
Supercomputer Linux Cluster for Genomics and Proteomics
The addition of a high-performance computing resource at NJH will allow the currently-funded NIH- sponsored studies in genetics, genomics, and proteomics the greatest opportunity for success in elucidating the genetic and molecular basis of pulmonary and immunologic disease in our patient populations. Abstract.
RO1 HL095393-01
09/24/08 - 07/31/12
NIH-NHLBI (PI Schwartz)
Genomic Signatures for Idiopathic Interstitial Pneumonia
The overall goal of this project is to combine genetic and genomic findings from patients with idiopathic interstitial pneumonia (IIP) to develop and validate phenotypically anchored molecular signatures that will serve to refine the diagnostic criteria for these diseases. Abstract
RO1-HL097163
07/01/09 - 06/30/14
NIH-NHLBI (PI Schwartz)
GWAS in Fibrosing Interstitial Lung Disease
The purpose of this proposal is to discover genetic variants that are central to the development of fibrosing interstitial lung diseases (fILD). Since both genetic variants and the environment increase the risk of disease development in fILD, we seek to comprehensively identify genetic variants associated with fILD by considering environmental exposures while studying the genetics of this group of complex diseases. Abstract
RO1-HL101251
07/01/09 - 6/30/14
NIH-NHLBI (PIs Cosgrove/Schwartz/Yang)
Asthma: an Epidemic Caused by Epigenetics?
The purpose of this proposal is to determine the extent to which epigenetic mechanisms contribute to the etiology of asthma in humans. The hypothesis pursued in this proposal is that epigenetic mechanisms play a fundamental role in the etiology of asthma by modulating the methylation state and transcriptional activity of critical genes that affect immune maturation and this then leads to the development of asthma. Abstract
P01-ES18181
09/01/09-08/31/14
NIH-NIEHS (PI Schwartz; Project 3 PDs Schwartz/Yang)
Environmental Determinants of Airway Disease in Children
The theme of this proposed Center is to investigate the etiology and pathogenesis of airway disease in children. Abstract
P01-HL092870
01/19/10-12/31/14
NIH-NHLBI (PD Schwartz)
Mechanisms of Familial Pulmonary Fibrosis; Gene and Environment Interactions in Pulmonary Fibrosis
The overall goal of Dr. Schwartz' project is to discover genetic variants that are central to the development of idiopathic interstitial pneumonia (IIP) by investigating combinations of genetic variations or polymorphisms interact with cigarette smoke and/or viruses to predispose individuals to the clinical development of pulmonary fibrosis. Abstract
N01-AI90052
09/30/09-11/30/14
NIH-NIAID - Inner City Asthma Consortium (PD Schwartz)
The Role of Epigenetics in Inner City Asthma
The overall goal of this proposal is to determine the extent to which epigenetic mechanisms contribute to the etiology of asthma in children living in the inner city. Abstract
RC2-HL101715
09/30/09-9/29/11
NIH-NHLBI (PIs Geraci/Kaminski/Quackenbush/Sciurba/Schwartz/Spira)
Lung Genomics Research Consortium
The overall goal of this project is to establish a genetic, molecular, and quantitative clinical phenotyping warehouse for the lung research community that would enable investigators to develop and test hypotheses to understand the etiology, pathogenesis, and clinical manifestation of complex, chronic lung diseases. Abstract
RC1-HD063508
09/30/09-9/29/11
NIH-NICHD (PIs Gelfand/Hauk/Schwartz)
Antenatal Dietary Supplementation is a Risk Factor for Infant Atopy through Epigenetics
Our hypothesis is that epigenetic mechanisms play a fundamental role in the etiology and induction of atopic disease by modulating the methylation state and transcriptional activity of critical genes. Abstract
RC1-HL099571
09/30/09-9/29/11
NIH-NHLBI (PIs Schwartz/Steele/Yang)
Peripheral Blood Biomarkers in Idiopathic Interstitial Pneumonia
The overall goal of this project is to develop peripheral markers of idiopathic interstitial pneumonia by characterizing the peripheral blood transcriptome. Abstract